2021 ieee16th international conference on industrial and information systems will be held from 8th to 11th of December 2021 as an online event. The conference is organized by the department of Electrical and Electronic Engineering, University of Peradeniya in collaboration with the Institute of Electrical and Electronic Engineers (IEEE). The conference consists of 5 keynote addresses conducted by prominent scholars from UK, Israel, India and Malaysia. A special session on 5G Evolution and 6G will be conducted by the Center for Wireless Communication in University of Oulu, Finland. Further, two workshops and a tutorial will be held in parallel to the conference. The conference has attracted papers from Australia, Japan, Taiwan, UK, USA, Canada, Finland, Singapore, India and Sri Lanka. The papers will be published in the IEEE xplore, which is accessible to over 3.5 million research and industry communities around the world.